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Jun 1, 2012
Canadian Animal Health Coalition Update
JD-ajdi2 May12.jpgJD-AJDI- Mar 12.jpgJD-ajdiMay 12.jpg

The CJDI Advisory and Technical Committees and management team have requested extended funding support for CJDI from DFC, CCA and other ruminant industries until 2014. This would allow time for Growing Forward 2 consideration and the address of remaining critical issues related to JD / MAP control in Canada.

Canadian JD control program updates:
 Atlantic JD Initiative updates are attached as scanned articles from The Milk Producer (March, 2012 and May, 2012).

 Ontario Johne’s Education and Management Assistance Program has reported that over 50% of ON herds and over 90,000 cows have been tested. Although MAP is likely present on many Ontario farms like the rest of North America, the number of identified positive cows (0.1+) in the Program (up until November, 2011) was low (0.7%) and the number of herds with at least one high titre cow (1.0+) was also low (7%). This reflects current testing capabilities and the biology of JD. Importantly the Program has identified and aided in the culling of the heavy MAP shedders, the high titre (1.0+) cows.

 SaskMilK is developing the Saskatchewan Dairy Herd Health and Screening Initiative to forward next month to the Canadian Agricultural Adaption Program. MAP testing of bulk milk and environmental manure samples, veterinary training, dairy herd risk assessments and management planning (RAMP) are key components. Partners would include SaskMilk, governments, UCVM, WCVM, and CanWest DHI. CJDI and other government – industry supporters have written letters of support.

 BCJDI has also recently received further Growing Forward funding for 2013-14 to continue validations of lab diagnostics and to conduct MAP and BVD testing on beef and dairy farms. The latter is done in conjunction with on-farm JD risk assessment and a best management plan.

The 5th Annual Map Researchers Meeting will be held October 11 - 13, 2012, at The Banff Centre, Banff. Discussions will include the potential for a national JD control program and creation of a Canadian MAP research network. The latter might test intervention strategies for Canadian herds with high MAP prevalence, as well as evaluate accurate, low cost, easy testing schemes and biosecurity recommendations for low prevalence herds. Such a research platform would enhance understanding of effective information / motivational tools for basic science oriented studies, as well as provide demonstration herds for regional JD initiatives.

Recent JD and MAP research excerpts from abstracts listed by the OIE (World Organization for Animal Health) Reference Laboratory for Paratuberculosis (Brno, Czech Republic), follow. Copies are available upon request.

 Cho, J., Tauer et al (2012). Economic analysis of MAP vaccines in dairy herds. J Dairy Sci, 95, 1855-1872… Two high-efficacy vaccines were particularly effective in MAP control… Only one high-efficacy vaccine, in which the vaccine is targeted at reducing MAP shedding and the number of clinical cases, was not economically beneficial to dairy producers compared with an alternative non-vaccine control, when herds were highly infected with MAP.

 Davis, W.C., Madsen-Bouterse, S.A. (2012). Crohn's disease and MAP: The need for a study is long overdue. Vet Immunology and Immunopathology, 145, 1-6. … Recent investigations have now revealed the presence of MAP or MAP DNA in blood or lesions from adults and children with CD… MAP has also been found in patients with other diseases as well as healthy subjects… all humans are susceptible to infection with MAP… infection does not invariably lead to development of clinical disease but rather development of a persistent latent stage of infection where an immune response controls but does not eliminate the pathogen. Understanding how MAP may be involved in the pathogenesis of CD will require a better understanding of the immune response to MAP in one of its common hosts, as well as healthy humans and patients with CD.

 Donahue, M. et al (2012). Heat treatment of colostrum on commercial dairy farms decreases colostrum microbial counts while maintaining colostrum immunoglobulin G concentrations. J Dairy Sci, 95, 2697… on commercial dairy farms in Minnesota and Wisconsin… batch heat treatment of colostrum at 60 C for 60 min… successfully decreased colostrum microbial counts while maintaining colostrum IgG concentrations.

 Fritsch, I. et al (2012). Suspicion of MAP Transmission between Cattle and Wild-Living Red Deer (Cervus elaphus) by Multitarget Genotyping. Applied and Enviro Micro, 78, 1132… wild-living and farmed animals maintain a reservoir for specific MAP genotypes… genotypes had been transmitted between and within species… one genotype had been transmitted between cattle herds only.

 Khol, J.L., Baumgartner, W. (2012). Examples and Suggestions for the Control of MAP in European Cattle. Jap J Vet Research, 60, S1… to harmonize the control of MAP in Europe… defined minimum standards suggested… 1) diagnostic evaluation of every case of diarrhea in adult cattle and culling of animals with clinical JD… 2) basic management measures… 3) regular evaluation of the MAP-herd status with the focus on MAP-shedding animals… reasonable costs and work load in most cattle herds… might serve as an international minimum standard for MAP-control in cattle.

 Giacometti, F. et al (2012). Sale of Raw Milk in Northern Italy: Food Safety Implications and Comparison of Different Analytical Methodologies for Detection of Foodborne Pathogens. Foodborne Pathogens and Disease, 9, 293… safety of raw milk… investigated… 3 samples (3%) were positive for MAP, suggesting that raw milk is a significant source of Map exposure for consumers.

 Slana, I. et al (2012). Examination of milk filters by real-time PCR as a herd-level indicator of the presence of MAP in dairy herds. J Dairy Sci, 95, 1162… probability of successful MAP detection in milk filters in a herd with MAP-infected cows is at least 94.3%... Analysis of milk filters for MAP can be a useful tool for the detection of MAP on the herd level before any individual control strategies.

 Stau, A., Ganter, M. (2012). Reactions to a vaccination against MAP and its side-effects on milk goats. Tieraerztliche Praxis Ausgabe Grosstiere Nutztiere, 40, 14… vaccination with Gudair (R) against JD... Goats… should not be vaccinated in the neck.

 Ware, J.K.W. et al (2012). Financial Effect of Bovine JD in Beef Cattle Herds in Australia. Australian Vet J, 90, 116… Eradication… more profitable in the longer term compared with living with the disease when discounts on the sale of stock from infected herds are high… In stud herds, JD will usually cause the total failure of the business.

Appendix i. CJDI Advisory Committee
 Pat Rutledge, Canadian Cattlemen’s Association (co-chair)
 Pauline Duivenvoorden, Dairy Farmers of Canada (co-chair)
 Louis Desautels, Canadian Cattlemen’s Association
 Réjean Bouchard, Dairy Farmers of Canada
 Ron Versteeg, Ontario Johne’s Education and Management Assistance Program
 Geneviève Côté, Comité directeur, Programme volontaire de prévention et de contrôle de la paratuberculose au Québec
 Herman Barkema (Technical Committee co-chair)
 Shawn McKenna (Technical Committee co-chair)

Appendix ii. CJDI Technical Committee
 Herman Barkema, University of Calgary (co-chair)
 Shawn McKenna, University of Prince Edward Island (co-chair)
 Gilles Fecteau, University of Montreal
 David Kelton, University of Guelph
 Steve Hendrick, University of Saskatchewan
 Reynold Bergen, Canadian Cattlemen’s Association
 Réjean Bouchard, Dairy Farmers of Canada
 Amanda Amaratunga, Canadian Food Inspection Agency
 Ann Godkin , Ontario Johne’s Education and Management Assistance Program
 Geneviève Côté, Comité directeur, Programme volontaire de prévention et de contrôle de la paratuberculose au Québec

Associated PDF's
CJDIupdate-May12.pdf
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